the difference between complete mole and partial mole
p57 expression

complete→46XX/XY enucleated egg+single sperm(subsequently duplicates paternal DNA)
no fetal parts, ↑↑↑↑hCG, 15-20% of malignancy
☆46XX(90%)>>46XY
*46YY cannot survive
proliferation of ☆cytotrophoblast
p57 is maternally expressed→ ☆p57 negative⇔ partial mole

partial→69XXX/XXY/XYY 2 sperm+1 egg
fetal parts,↑hCG,<5% of malignancy

reproductive OBGY UWorld SIM2