easy bruising and hemarthrosis accompanied with Crohn disease☆bile acid malabsorption
→ fat malabsorption
→ vitamine K deficiency gastrointestinalhematologyUWorld Jul 9, 2020, 1:02 AM HirotoShishido
type of Hodgkin lymphoma・Nodular sclerosis
Most common
・Lymphocyte rich
Best prognosis
・Mixed cellularity
Eosinophilia, seen in immunocompromised patients
・Lymphocyte depleted
Seen in immunocompromised patients hematology Jul 5, 2020, 10:26 PM HirotoShishido
erythropoietin in polycythemia vera(PV)
EPO decreases due to negative feedback suppressing renal EPO production hematology Jul 3, 2020, 9:10 PM HirotoShishido
prothrombin gene mutationMutation in 3′ untranslated region →↑production of prothrombin → ↑plasma levels and venous clots. hematology Jul 3, 2020, 7:29 AM HirotoShishido
affinity of hemoglobin A and F to oxygenFetal hemoglobin (hemoglobin F) is synthesized primarily during fetal development (-8 weeks until term) and consists of the usual 2 alpha chains with 2 gamma chains in place of beta chains. The gamma chains do not bind effectively to 2,3-BPG due to replacement of a ☆histidine residue with serine. hematologyUWorld Jul 3, 2020, 6:07 AM HirotoShishido
